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Fenofibrate 135mg
Medically Reviewed by – Kyle Patterson, PharmD
Last Updated on 8 July 2026

Fenofibrate 135mg

$1.09 $1.33
Fenofibrate 135mg is a medication used to lower high levels of cholesterol and triglycerides in the blood. It belongs to the fibrate class of drugs, which work by breaking down fatty substances, reducing the risk of heart disease and pancreatitis. This medication helps increase good cholesterol (HDL) while lowering bad cholesterol (LDL) and triglycerides. It is typically prescribed to individuals who do not respond well to diet and exercise alone. Fenofibrate 135mg is often used alongside lifestyle changes, such as a low-fat diet and regular exercise, to improve overall heart health.
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Categories: CholesterolTag: Pills

What is Fenofibrate 135mg?

Fenofibrate 135mg is a medication used to lower high levels of cholesterol and triglycerides in the blood. It belongs to the fibrate class of drugs, which work by breaking down fatty substances, reducing the risk of heart disease and pancreatitis. This medication helps increase good cholesterol (HDL) while lowering bad cholesterol (LDL) and triglycerides. It is typically prescribed to individuals who do not respond well to diet and exercise alone. Fenofibrate 135mg is often used alongside lifestyle changes, such as a low-fat diet and regular exercise, to improve overall heart health.

How to Use Fenofibrate 135mg?

  • Take Fenofibrate 135mg exactly as prescribed by your doctor.
  • Swallow the tablet whole with a glass of water, preferably with food.
  • Do not crush, chew, or break the tablet.
  • If you miss a dose, take it as soon as you remember, unless it’s close to the next dose. Never double up.
  • Regular blood tests may be needed to monitor your cholesterol and triglyceride levels.
  • Keep following a healthy diet and exercise routine while taking this medication for the best results.

Dosage Instructions

  • Standard dose: One Fenofibrate 135mg tablet daily with a meal.
  • Adjustments: Your doctor may modify the dose based on your response to treatment.
  • Special cases: People with kidney issues may require a lower dose.
  • Overdose risk: Taking too much can lead to severe muscle pain, nausea, or abdominal discomfort. Seek medical attention if you suspect an overdose.

Never change the dosage on your own. Always follow your doctor’s instructions.

Side Effects

Fenofibrate 135mg is generally well-tolerated, but some people may experience side effects, such as:

  • Stomach pain, nausea, vomiting, or diarrhea
  • Headache or dizziness
  • Muscle pain, weakness, or tenderness
  • Increased liver enzyme levels (seen in blood tests)

Serious side effects are rare but may include rhabdomyolysis (severe muscle damage), liver problems, or an allergic reaction. Seek medical help if you notice yellowing of the skin, dark urine, or unusual muscle pain.

Drug Interactions

Fenofibrate 135mg may interact with certain medications, leading to potential risks:

  • Statins (e.g., Simvastatin, Atorvastatin): Increased risk of muscle damage.
  • Blood thinners (e.g., Warfarin): Can raise the risk of bleeding.
  • Diabetes medications (e.g., Insulin, Metformin): May enhance blood sugar-lowering effects.
  • Immunosuppressants (e.g., Cyclosporine): Can impact kidney function.

Tell your doctor about all the medications, vitamins, or supplements you are taking to avoid harmful interactions.

Warnings

Before taking Fenofibrate 135mg, consider these precautions:

  • Liver or kidney disease: Avoid use if you have severe conditions.
  • Gallbladder disease: This medication may increase the risk of gallstones.
  • Pregnancy & breastfeeding: Not recommended unless prescribed by a doctor.
  • Allergies: Do not take if you’ve had an allergic reaction to fibrates before.

Routine health check-ups and blood tests help ensure the medication is working safely.

Storage

  • Keep Fenofibrate 135mg at room temperature (68-77°F or 20-25°C).
  • Store away from moisture, heat, and direct sunlight.
  • Avoid keeping it in the bathroom or near a sink.
  • Keep out of reach of children and pets.
  • Dispose of expired or unused tablets properly, following local guidelines.

FAQ

What to avoid when taking Fenofibrate 135mg?

Avoid excessive alcohol consumption, as it may increase triglycerides and liver strain. Also, steer clear of high-fat foods, as they can counteract the medication’s effects. If taking other cholesterol-lowering drugs, consult your doctor to prevent interactions.

When is the best time to take Fenofibrate 135mg?

Fenofibrate 135mg should be taken with a meal to improve absorption. While some people take it at night to align with the body’s natural lipid production, the timing is flexible as long as it’s taken consistently.

How fast does Fenofibrate 135mg lower triglycerides?

Results vary, but noticeable improvements in triglyceride levels are often seen within a few weeks to three months. Regular blood tests help track progress and adjust the dosage if needed.

Is Fenofibrate 135mg available over the counter?

No. Fenofibrate 135mg is not available over the counter. It is a prescription-only medicine, so it should be used only after a licensed healthcare provider confirms it is suitable for your condition and explains the correct dosage, precautions, and possible interactions.

Is there a Coupon for Fenofibrate 135mg?

Yes, International Drug Mart offers savings options for Fenofibrate 135mg, helping patients manage medication costs more efficiently. Pricing may vary by pack size, but promotional discounts support affordability and convenient home delivery across the U.S.

Is Fenofibrate 135mg a prescription medication?

Yes. Fenofibrate 135mg is a prescription medication. It should be taken only when prescribed by a licensed healthcare provider. Do not start, stop, or change the dose without medical advice.

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