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Prednisone/Prednisolone

Prednisone/Prednisolone

Prednisone is a corticosteroid drug used to treat different conditions such as allergic disorders, immune system diseases, chronic obstructive pulmonary disease, psoriasis, skin problems, ulcerative colitis, spinal cord injuries, eye problems, arthritis, lupus, organ transplantation, and Addison's disease. This medicine may also be used to treat other conditions as determined by your doctor.    
Category: Allergies
Medically Reviewed by – Millie Chapman, NP
Last Updated on 8 July 2026

What is Prednisone used for?

Prednisone is a corticosteroid drug used to treat different conditions such as allergic disorders, immune system diseases, chronic obstructive pulmonary disease, psoriasis, skin problems, ulcerative colitis, spinal cord injuries, eye problems, arthritis, lupus, organ transplantation, and Addison's disease. This medicine may also be used to treat other conditions as determined by your doctor.

What are the side effects of Prednisone?

Prednisone may cause certain unwanted effects, especially with long-term or high-dose use. Common reactions often settle as your body adjusts, but speak with your GP if they persist or worsen.
  • Increased appetite and possible weight gain
  • Difficulty sleeping or mood changes
  • Indigestion or stomach upset
  • Puffiness in the face (moon face)
  • Thinning skin and slower wound healing
  • Muscle weakness or cramps
  • Raised blood pressure or blood sugar levels

What is the recommended dosage of Prednisone?

The dosage of Prednisone prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label. Take Prednisone by mouth, along with food to prevent stomach upset.

What if you miss a dose of Prednisone?

If your physician has instructed or directed you to take Prednisone medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Prednisone?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Prednisone, seek medical attention immediately.

What other drugs could interact with Prednisone?

It may be noted that drugs other than those listed above may also interact with Prednisone. Usually, drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about the intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Prednisone, and dietary supplements like vitamins, minerals, and herbal, so that the doctor can warn you of any possible drug interactions. Prednisone can interact with blood thinners, diabetes medications, and seizure medications. Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

Can you buy prednisone over the counter in UK?

No, you cannot buy Prednisone over the counter in the UK. It is a prescription-only medicine because it can cause serious side effects if not used correctly. A doctor must assess your condition and decide the right dose and duration of treatment. Pharmacies will only supply Prednisone when you present a valid NHS or private prescription. If you believe you need this medicine, speak to your GP or a healthcare professional for proper guidance and monitoring.

Can I buy Prednisone without a prescription in UK?

No, you cannot buy Prednisone without a prescription in the UK. It is a controlled prescription medicine, used to treat conditions such as asthma, arthritis, and autoimmune disorders. Because of its potential side effects, Prednisone must be taken under medical supervision. Pharmacies will not sell it without a valid prescription from a registered doctor. If you think you need this medicine, consult your GP for an assessment and an appropriate treatment plan tailored to your health condition.

Can I buy Prednisolone online in UK?

Yes, you can buy Prednisolone online in the UK, but only with a valid prescription. Reputable online pharmacies registered with the General Pharmaceutical Council (GPhC) can supply it once a doctor approves your order. You may complete an online consultation where a licensed healthcare professional reviews your details before issuing a prescription. Avoid unverified websites offering Prednisolone without prescription, as these may sell unsafe or counterfeit medicines. Always ensure you’re buying from a trusted UK-registered pharmacy.

Where can i buy prednisone in UK ?

You can buy Prednisone or Prednisolone in the UK only from licensed pharmacies or trusted online platforms after a valid doctor’s prescription. Reputable sites like InternationalDrugMart.com offer genuine medicines with secure delivery. Always ensure the pharmacy is GPhC-registered and avoid unverified sellers, as they may provide unsafe or counterfeit products not approved for UK medical use.

What are the questions to ask your doctor before taking Prednisolone ?

Is it possible for me to take Prednisone with other drugs? Should certain beverages, foods and other products be avoided when I take Prednisone? What are the possible drug interactions of Prednisone? How will Prednisone work in my body? How should Prednisone be taken? How to reduce the risk of Prednisone drug interactions and side effects?

Note

The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Prednisone is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.

FAQ'S:

Is prednisone a powerful steroid?

Yes, prednisone is a powerful corticosteroid used to reduce inflammation and suppress the immune system. It is commonly prescribed to treat various conditions like allergies, asthma, autoimmune diseases, and arthritis. It’s essential to follow your doctor’s instructions carefully due to its strong effects and potential side effects.

What to avoid while taking Prednisolone?

Avoid alcohol, as it can increase the risk of gastrointestinal bleeding. Limit intake of high-sodium and high-sugar foods, as prednisone can cause fluid retention and elevated blood sugar levels. Also, avoid live vaccines, as prednisone weakens your immune system, making it harder for your body to fight infections.

Who cannot take prednisone?

People with fungal infections, uncontrolled diabetes, osteoporosis, or high blood pressure may not be suitable for prednisone. Those allergic to prednisone or any of its components should also avoid it. Always consult a doctor for a complete evaluation to determine if prednisone is safe for you.

What exactly does Prednisolone do to the body?

Prednisone works by suppressing the immune system and reducing inflammation, helping control symptoms like pain, swelling, and allergic reactions. However, long-term use can lead to side effects like weight gain, high blood pressure, mood swings, and weakened bones, so it's typically used for short durations.

What diseases is prednisone used to treat?

Prednisone is used to treat various conditions, including asthma, rheumatoid arthritis, lupus, inflammatory bowel disease, severe allergies, and multiple sclerosis. It is also prescribed for autoimmune diseases and skin disorders, as well as to reduce inflammation in other medical conditions like respiratory infections.

What is the average price of prednisone?

The price of prednisone varies based on dosage, brand, and pharmacy location. Generally, a 30-day supply of generic prednisone tablets may cost around $10-$40 without insurance. Brand-name versions or higher doses might be more expensive. It's advisable to check with your pharmacy for accurate pricing.

Is prednisone for sale online in UK?

Prednisone is available for sale online in the UK, but only through licensed pharmacies that require a valid doctor’s prescription. You can complete an online consultation, and once approved, the medicine will be dispensed by a registered UK pharmacy. Avoid websites offering Prednisone without a prescription, as these may not meet safety standards. Ensure the medicine is genuine and supplied under proper medical supervision for your condition.

What are the variants are there in prednisone/Prednisolone?

Prednisone and Prednisolone are available in several strengths and forms to suit different medical needs. At International Drug Mart, you can find the following variants:

These formulations are offered to meet varying dosage requirements under medical supervision.

Can i order prednisone online in the UK?

Yes, you can order Prednisone online in the UK through trusted, regulated pharmacies. Before purchasing, you’ll need to complete a short health questionnaire reviewed by a licensed clinician. Once approved, the prescription is processed, and your medicine is delivered safely to your address. Always choose GPhC-registered pharmacies to ensure quality and genuine products.

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