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Mupirocin

Mupirocin

Mupirocin is an antibiotic ointment used to treat or prevent certain bacterial skin infections such as impetigo. This topical (applied onto the skin) medication works by stopping the growth of bacteria. This medicine may also be used to treat other conditions as determined by your doctor.
Category: Anti Biotics
Medically Reviewed by – Brandon Hayes, PharmD
Last Updated on 8 July 2026

What is Mupirocin used for?

Mupirocin is an antibiotic ointment used to treat or prevent certain bacterial skin infections such as impetigo. This topical (applied onto the skin) medication works by stopping the growth of bacteria. This medicine may also be used to treat other conditions as determined by your doctor.

What are the side effects of Mupirocin?

Like other medicines, Mupirocin can cause some side effects. If they do occur, the side effects of Mupirocin are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Mupirocin cannot be anticipated. If any side effects of Mupirocin develop or change in intensity, the doctor should be informed as soon as possible.

Mupirocin can cause side effects such as stinging, burning, itching, dryness, redness, peeling, and skin irritation. Some of the uncommon side effects of this drug are dizziness, abdominal pain, and mouth sores. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are using Mupirocin.

What is the recommended dosage of Mupirocin?

The dosage of Mupirocin prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label. The following dosage information includes the common dose of Mupirocin. If your dose is different, do not follow the dosage described below unless your physician has approved.

A small amount of Mupirocin ointment should be applied onto the affected area three times daily. Before applying the medicine, clean and dry the affected area. Wash your hands before and after using this medication.

What if you miss a dose of Mupirocin?

If your physician has instructed or directed you to apply Mupirocin medication in a regular schedule and you have missed a dose of this medicine, apply it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Mupirocin?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Mupirocin, seek medical attention immediately.

What other drugs could interact with Mupirocin?

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Mupirocin, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Mupirocin can interact with other topical preparations.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor

FAQ’S

What happens if you put mupirocin on an open wound?

Mupirocin can be applied to an open wound to help prevent or treat infection. It works by stopping bacteria from growing in the wound, which helps speed up healing. However, it’s important to follow your healthcare provider’s instructions and use it only for the prescribed duration.

Is mupirocin a strong antibiotic?

Yes, mupirocin is a strong topical antibiotic effective against certain skin infections caused by bacteria, including Staphylococcus aureus and Streptococcus pyogenes. It’s often used for skin conditions like impetigo or infected wounds. It should only be used under a healthcare provider’s guidance.

How quickly does mupirocin work?

Mupirocin generally starts working within a few days of application. Improvement is often seen within 3 to 5 days, but the full course should be completed to ensure the infection is fully treated. If symptoms worsen or do not improve, consult your healthcare provider.

Where should you not use mupirocin ointment?

Mupirocin should not be applied inside the nose, eyes, or mouth, as it can cause irritation. It’s also not recommended for use on large, deep wounds, severe burns, or areas where the skin is broken unless directed by a healthcare professional. Always follow your provider’s instructions.

Is Mupirocin Ointment and Cream available over the counter?

No. Mupirocin Ointment and Cream is not available over the counter. It is a prescription-only medicine, so it should be used only after a licensed healthcare provider confirms it is suitable for your condition and explains the correct dosage, precautions, and possible interactions.

Can you use mupirocin cream on your face?

Yes, mupirocin cream can be used on the face, but it should only be applied as directed by your healthcare provider. Avoid contact with your eyes, nose, or mouth. It is used to treat bacterial skin infections and should be used with caution on sensitive areas like the face.

Is Mupirocin Ointment and Cream a prescription medication?

Yes. Mupirocin Ointment and Cream is a prescription medication. It should be taken only when prescribed by a licensed healthcare provider. Do not start, stop, or change the dose without medical advice.

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