Sertraline vs Wellbutrin

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Weight Impact
Energy & Motivation
Prescription Required
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Popular Brands in the USA
Frequently Asked Questions
Is Wellbutrin and sertraline a good combination?
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Yes, Wellbutrin and sertraline are sometimes prescribed together. This combo may balance serotonin, dopamine, and norepinephrine levels, helping improve mood and energy. Wellbutrin may also reduce some side effects of sertraline, like sexual dysfunction. However, combining them can increase the risk of side effects, so doctors monitor closely. Always follow your healthcare provider's advice.
What can sertraline not be mixed with?
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Sertraline should not be mixed with monoamine oxidase inhibitors (MAOIs), other SSRIs, or certain migraine medications, as this may increase serotonin levels too much. It also interacts with blood thinners, antipsychotics, and alcohol. Mixing with illegal drugs or some supplements like St. John's Wort could cause harmful effects. Always consult your doctor before combining medicines.
What cannot be mixed with Wellbutrin?
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Wellbutrin should not be mixed with other medications that lower the seizure threshold, like some antipsychotics, steroids, or stimulants. Avoid drinking large amounts of alcohol, as it increases seizure risk. It\'s also risky to combine Wellbutrin with MAOIs or nicotine patches without medical advice. Always tell your doctor about all drugs, supplements, or alcohol use.
What does it feel like when Wellbutrin starts working?
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When Wellbutrin starts working, some people feel more energetic, motivated, and focused. Mood may gradually lift, and interest in daily activities may return. This effect usually begins after 1 2 weeks but full results take longer. Some feel slightly restless or have trouble sleeping at first, but these symptoms often fade. Results vary from person to person.
Can you still feel love on sertraline?
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Yes, you can still feel love while taking sertraline. But for some people, the drug may reduce emotional intensity or sexual desire. This side effect varies widely. Some people feel emotionally "blunted," while others feel more stable and connected to loved ones. If emotional changes bother you, talk to your doctor about adjusting the dose.


