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Acyclovir

Acyclovir

Acyclovir is an antiviral drug prescribed to treat infections such as chickenpox, genital herpes, shingles and cold sores, which are caused by herpes viruses. It decreases the growth and spread of herpes virus in the body and helps faster healing of sores. Acyclovir eye ointment is used to treat viral eye infections caused by herpes simplex viruses. Acyclovir is available as tablet, topical cream and eye ointment forms. This medicine may also be used to treat other conditions as determined by your doctor.
Category: Anti Virals
Medically Reviewed by – Dr. Bailey Morrison, MD
Last Updated on 8 July 2026

What is Acyclovir used for?

Acyclovir is commonly used in Australia to treat infections caused by the herpes virus, such as cold sores, genital herpes, shingles, and chickenpox. It works by slowing the growth and spread of the virus, helping sores heal faster and reducing pain or itching. Although it doesn’t cure herpes, it helps control symptoms and lowers the chance of future outbreaks.

What are the acyclovir side effects?

Common side effects of Acyclovir are usually mild and temporary. However, some people may experience the following:

  • Headache or dizziness

  • Nausea, vomiting, or diarrhoea

  • Tiredness or general weakness

  • Skin rash or itching

  • Changes in mood or confusion (rare)

  • Kidney issues in people with existing problems

If symptoms persist or worsen, seek medical advice promptly.

What is the recommended dosage of Acyclovir?

The recommended dosage of Acyclovir varies depending on the infection being treated and your health condition. Always follow your doctor’s directions. Common guidelines include:

  • Cold sores or genital herpes: 200mg to 400mg taken five times a day

  • Shingles: 800mg every four hours, five times daily

  • Chickenpox: 800mg four times daily for five days

Always complete the full course for best results.

What if you miss a dose of Acyclovir?

If your physician has instructed or directed you to use Acyclovir medication in a regular schedule and you have missed a dose of this medicine, use it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Acyclovir?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Acyclovir, seek medical attention immediately.

What other drugs could interact with Acyclovir?

It’s worth noting that other medicines not mentioned here may also interact with Acyclovir. Drug interactions can occur when it’s taken alongside other medications or certain foods. Before beginning treatment, let your healthcare provider know about any other medicines you’re taking — including over-the-counter products, vitamins, minerals, or herbal supplements — so they can give proper advice. Acyclovir can interact with nonsteroidal anti-inflammatory drugs (NSAIDs). Be sure to tell your doctor if you smoke, drink alcohol, have caffeine, or use recreational drugs, as these may influence how your medication works. Always inform your doctor about any existing health conditions or family medical history, and never start or stop taking any medication without their guidance.

Where can I buy Acyclovir over the counter in Australia?

In Australia, Acyclovir is usually available at local chemists or online pharmacies, but only some lower-strength creams may be sold without a prescription. Tablets and higher doses typically require a doctor’s prescription. It’s best to speak with your pharmacist or healthcare provider to find the most suitable and legal way to purchase Acyclovir safely.

Can I buy Acyclovir without a prescription in Australia?

In Australia, you can only buy certain Acyclovir creams for cold sores without a prescription. However, Acyclovir tablets and higher-strength forms require a doctor’s prescription. This ensures proper diagnosis and safe use. Always check with your pharmacist or healthcare provider before purchasing to make sure you’re following Australian medication guidelines.

Dose acyclovir for herpes zoster in adults?

The usual Acyclovir dose for herpes zoster (shingles) in adults — in Australian English (Aussie accent) — is typically 800 mg taken five times a day, roughly every four hours while awake, for seven days. It’s important to start treatment as soon as the rash appears for best results. Always follow your doctor’s directions and keep well-hydrated during the course.

What are the questions to ask your doctor before taking Acyclovir tablet?

Is it possible for me to use Acyclovir with other drugs? Should certain beverages, foods and other products be avoided when I use Acyclovir? What are the possible drug interactions of Acyclovir? How will Acyclovir work in my body? How should Acyclovir be used? How to reduce the risk of Acyclovir drug interactions and side effects?

Note

The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Acyclovir is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.

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