International Drug Mart

Losartan vs Metoprolol

Losartan vs Metoprolol

Classification

Angiotensin II receptor blocker (ARB)
Beta-blocker

Indications

Hypertension, Diabetic nephropathy
Hypertension, Angina, Heart failure, Heart attack

Mechanism of Action

Blocks angiotensin II receptors, reducing vasoconstriction and aldosterone secretion
Blocks beta-adrenergic receptors in the heart, reducing heart rate and cardiac output

Common Side Effects

Dizziness, Upper respiratory infections, Nasal congestion, Back pain
Fatigue, Dizziness, Depression, Shortness of breath, Bradycardia

Serious Side Effects

Angioedema, Kidney failure, Hyperkalemia
Heart block, Severe bradycardia, Heart failure exacerbation, Hypotension

Contraindications

Hypersensitivity to losartan, Pregnancy
Severe bradycardia, Heart block, Cardiogenic shock, Severe asthma

Typical Dosage

25-100 mg daily in 1 or 2 divided doses
25-100 mg daily in 1 or 2 divided doses

Drug Interactions

Potassium supplements, NSAIDs, Lithium
Other beta-blockers, Calcium channel blockers, Antidepressants

Considerations

May be preferred in patients with diabetes for kidney protection
Preferred in patients with prior heart attack or chronic heart failure

Cost without insurance

Generally lower cost than metoprolol
Generally higher cost compared to losartan
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Frequently Asked Questions

What is the main difference between Losartan and Metoprolol?

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Losartan is an angiotensin II receptor blocker (ARB), while Metoprolol is a beta-blocker. Losartan lowers blood pressure by relaxing blood vessels, whereas Metoprolol reduces heart rate and workload on the heart.

Can I take Losartan and Metoprolol together?

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Yes, they are often prescribed together to manage high blood pressure or heart conditions. However, your doctor will monitor you closely for side effects like low blood pressure or dizziness.

Which is better for high blood pressure, Losartan or Metoprolol?

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Both can be effective, but the best choice depends on your overall health. Losartan may be preferred for patients with kidney issues, while Metoprolol might be chosen for those with certain heart conditions.

Do Losartan and Metoprolol have different side effects?

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Yes. Losartan may cause dizziness or high potassium levels. Metoprolol can lead to fatigue, slow heart rate, or cold extremities. Side effects vary per individual.

Are there any conditions where one is preferred over the other?

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Yes. Losartan is often used in people with diabetes or kidney disease. Metoprolol is preferred for heart rhythm issues or after a heart attack. Always follow your doctor's recommendation.

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